Dynamics of the FK3V cardiac cell model

Ing. Radek Halfar

Katedra kybernetiky a biomedicínského inženýrství, VŠB-TU Ostrava


dne 13.6.2017 od 12:30
na EB226 (nová FEI)
VŠB-TU Ostrava
17.listopadu 15
v Ostravě-Porubě

Abstrakt

The aim of this paper is to study evolution of transmembrane potencial on the cardiac cell under different rates of stimulation. For modeling this potential, the Fenton-Karma model was applied. It is a phenomenological model with three degree of freedom that corresponds to nondimensional transmembrane potencial and gating variables for regulation of inward and outward ion currents. Moreover, as a novelty, the model was forced by stimulus with shape of half sinus period. For solving the equations the explicit Runge-Kutta method was used. As the main aim of the paper it is shown that that the Fenton-Karma model is showing regular as well as irregular motion; periodic and also chaotic patterns are detected using bifurcation diagrams and 0-1 test for chaos.